Serum immunoglobulin E and absolute eosinophil count as markers of severity in childhood asthma
نویسندگان
چکیده
منابع مشابه
Correlation of total serum immunoglobulin E level, sputum, and peripheral eosinophil count in assessing the clinical severity in bronchial asthma
CONTEXT Asthma is a chronic inflammatory disorder of the airway with involvement of various cellular populations and release of many inflammatory mediators. Eosinophils and serum immunoglobulin E (IgE) are considered a good marker of airway inflammation in asthma. The correlation of clinical assessment with various markers of airway inflammation in asthma is not well established in the Indian p...
متن کاملCorrelation of immunoglobulin E, eosinophil cationic protein, and eosinophil count with the severity of childhood perennial allergic rhinitis.
BACKGROUND AND PURPOSE Elevated levels of serum total immunoglobulin E (IgE), serum allergen-specific IgE, serum eosinophil cationic protein (ECP), blood eosinophil count and nasal eosinophil count are considered to be associated with allergic rhinitis (AR), but the relationships between these allergic inflammatory markers and the clinical severity of AR remain controversial. This study aimed t...
متن کاملChanges in serum eotaxin and eosinophil cationic protein levels, and eosinophil count during treatment of childhood asthma.
BACKGROUND AND PURPOSE Increased serum levels of eotaxin are related to the severity of asthma in adults. There are limited data on the effects of oral corticosteroids and inhaled corticosteroid therapy on serum levels of eotaxin and eosinophil cationic protein (ECP) and peripheral blood eosinophil counts (ECs) in pediatric asthma patients. We investigated prospectively the changes in eotaxin a...
متن کاملAssociation of inducible nitric oxide synthase with asthma severity, total serum immunoglobulin E and blood eosinophil levels.
BACKGROUND Nitric oxide is released by immune, epithelial and endothelial cells, and plays an important part in the pathophysiology of asthma. OBJECTIVE To investigate the association of inducible nitric oxide synthases (iNOS) gene repeat polymorphisms with asthma. METHODS 230 families with asthma (842 individuals) were recruited to identify and establish the genetic association of iNOS rep...
متن کاملSerum levels of IL-17A increase in Asthma but not in accordance with Serum level of IgE and Asthma Severity
Background and Aims: Recent evidence suggests that T helper (Th) 17 cells are involved in the emergence of asthma. Th17 cells have a key role in inducing inflammation in asthmatic airways thus Interleukin (IL)-17A, the main cytokine of Th17, contributes to airways inflammation. Materials and Methods: We evaluated the level of IL-17A and total immunoglobulin E (IgE) in sera of 100 asthmatic p...
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ژورنال
عنوان ژورنال: International Journal of Contemporary Pediatrics
سال: 2020
ISSN: 2349-3291,2349-3283
DOI: 10.18203/2349-3291.ijcp20200120